Population Recommended Oral Dose Adults, aged 18 years and older 3 grams or less QD for up to eight weeks Adults at risk for cardiovascular diseas e 3 grams QD for up to eight weeks Children (age <18) Insufficient evidence available Cachexia 3 grams HMB + 14 grams arginine + …
Objectives. The aim of this meta-analysis was to examine the evidence for the effectiveness of beta-hydroxy-beta-methylbutyrate supplementation interventions on modification in strength and body composition in trained and competitive athletes.
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Jan 03, 2008· The efficacy of HMB supplementation for untrained participants. Nissen et al.  examined the effects of HMB on muscle metabolism and performance during resistance-exercise in two experiments in healthy untrained males.Participants in the first experiment ingested 0, 1.5, or 3 g of HMB daily, while weight lifting 3 days per week for 3 weeks.
β-Hydroxy β-methylbutyric acid (HMB), otherwise known as its conjugate base, β-hydroxy β-methylbutyrate, is a naturally produced substance in humans that is used as a dietary supplement and as an ingredient in certain medical foods that are intended to promote wound healing and provide nutritional support for people with muscle wasting due to cancer or HIV/AIDS.
There is some evidence that this innovative nutrient can raise anabolism (the constructive phase of metabolism) and promote recovery in trained athletes. As well, there may be some other beneficial effects for the endurance athlete who chooses to use this novel supplement. HMB stands for beta-hydroxy-beta-methyl butyrate.
HMB, 3-hydroxy-3-methyl butyrate, is of interest as a dietary supplement and a possible component of functional and medical foods. The purpose of this study was to evaluate the toxicity of the .
Keywords:Beta-hydroxy-beta-methyl butyrate, elderly, muscle function, muscle mass, muscle wasting, leucine, sarcopenia. Abstract:β-hydroxy-β-methylbutyrate (HMB) is a metabolite derived from leucine and its ketoacid alpha- ketoisocaproate. Leucine has a role in regulating protein synthesis in muscle cells, and HMB seems to be a key active .